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March 7
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myALZteam

How can you understand the decline in your husband's SLUMS test scores while on memantine?

It's understandable to feel concerned about this significant decline in test scores. Memantine is designed to help manage symptoms of moderate to severe Alzheimer's, but it doesn't stop the disease from progressing. The medication Show Full Answer

How can you understand the decline in your husband's SLUMS test scores while on memantine?

It's understandable to feel concerned about this significant decline in test scores. Memantine is designed to help manage symptoms of moderate to severe Alzheimer's, but it doesn't stop the disease from progressing. The medication works by regulating glutamate in the brain, which can help with symptoms, but Alzheimer's is a progressive condition that continues to advance over time.

A drop from 18 to 5 on the SLUMS test over three years indicates that cognitive abilities have declined considerably despite treatment. This progression is unfortunately part of the disease course for many people.

Here are some things to consider:

- Memantine may be helping slow symptoms, but the disease itself continues to progress
- The medication is most effective when started early and works best for managing current symptoms rather than preventing decline
- Cognitive tests like SLUMS help doctors track progression and adjust care plans accordingly

It's important to discuss these results with your husband's doctor. They may want to review his current treatment plan, assess whether the memantine dosage is appropriate, or consider adding other medications like cholinesterase inhibitors if not already prescribed.

You're not alone in this journey - many caregivers experience similar concerns as they watch their loved ones progress through different stages of Alzheimer's.

March 7
A myALZteam Member

My dad is on it 10mg every day. Seems to be working from progressing this awful disease.. My mom on the other hand takes 10mg 2x a day, it doesn't seen to help her much... So I guess it depends on the individual.

March 9
A myALZteam Member

My husband was on it for several years. Hard to tell if it helped. He passed away in February. I stopped giving it to him about three years ago.

March 8
A myALZteam Member

My dad was on it for a while. I'm not really sure if it helped or not. My dad died Dec 15th. Just be there with him and give him lots of good love. Enjoy the time you have with him.

March 8

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