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Real members of myALZteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myALZteam Member asked a question 💭
Barrington, IL

Donepezil was prescribed for my husband who is in early stage AD. We started with 5 mg. and after 6 months increased it to 10mg. He took it at bedtime and never had an adverse reaction. With the increase to 10mg. he experienced nightmares and diarrhea. The doc said to stop all and start over with 5 for a month and take it in the morning. Now, it is time to increase it again but I'm not sure if that is a good idea. Anyone else have this problem with 10mg ?

August 31, 2018
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Answer Summary

Members connected over the challenging decision of adjusting Aricept dosage for loved ones with Alzheimer's, with many reporting that... Read more

Members connected over the challenging decision of adjusting Aricept dosage for loved ones with Alzheimer's, with many reporting that switching the medication from bedtime to morning helped reduce nightmares and other side effects while maintaining effectiveness at the 10mg dose. Several members shared practical alternatives when side effects persisted, including switching to the Exelon patch combined with Namenda, reducing back to 5mg permanently, or waiting a few weeks to see if side effects naturally subside. A recurring theme was the difficult balance between fear of not medicating and concern over quality of life, with members emphasizing the importance of working closely with doctors, being patient with trial and error, and celebrating small victories on good days.

A myALZteam Member

My husband also early stage started on 5mg for a month and there was a noticeable improvement so he was then increased to 10mg. This.made him agitated, restless and hallucinate he also had problems sleeping .We were advises by doctor to reduce to 5mg and remain at this dose permanently . This was 6 months ago and seems to be ok. Hope that helps

October 15, 2018
A myALZteam Member

My mum struggled with bad dreams, we swapped to morning and kept at 10mg and she’s fine.

September 17, 2018
A myALZteam Member

Often, the side effects subside after a few weeks.

August 31, 2018
A myALZteam Member

My wife took to it very well, but not everyone does. She has always taken it mornings. In the first few weeks at 10mg she said her head felt “ full”. No problems since. All best, S

August 31, 2018 (edited)
A myALZteam Member

My father started with Ariceft but began with the agitation. The sr seems to think it’s the disease but we took him off he was only on it for about 2 mos. How long will it take to get out of his system to see if it was the medication. ? He was on the 5 mg for about 6 weeks and 10 mg 2 weeks

July 20, 2025

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