Does Memantine And Donepezil Help With Vascular Dementia | myALZteam

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Does Memantine And Donepezil Help With Vascular Dementia

A myALZteam Member

posted November 14, 2021
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9 replies
A myALZteam Member

I had horrible nightmares and kept on all night. I got off both and I take 15mg of melatonin before bedtime and I sleep very well.

posted November 5, 2022
A myALZteam Member

My sister had the same experience with the donepezil - nightmares would not take it after that. On menmantine for two months. So far no major effects

posted November 29, 2021
A myALZteam Member

We tried it. At first he had some severe diarrhea. stopped it for several days then tried again. This time he has some very vivid and realistic nightmares. He is just alert enough to relate the dreams to the pill and will not take it again.

posted November 28, 2021
A myALZteam Member

Varies based on person ,but my sister has been on for a month and it has made a noticeable difference. (memantine) Donepzil gave her bad dreams

posted November 20, 2021
A myALZteam Member

Everyone is different

posted November 15, 2021
A myALZteam Member

I’m grateful for all the information that is shared. My husband has been on both for the past year. However I’ve noticed an increase in irritability and confusion when he takes Donepezil. I’ve stopped it for a while, but now that I started giving it to him again, I think that those symptoms has gotten worse. I will follow up with the doctor to see where I go from here.

posted November 14, 2021
A myALZteam Member

Yes I think it does

posted November 14, 2021
A myALZteam Member

My husband is diagnosed with vascular Dementia and has been taking Donepezil for almost 4years. Donepezil was the first medication he was prescribed. At first he had lost of his appetite, but I adjusted from after breakfast to after dinner and it helped. He's had a great appetite since and i do believe it has prolonged his dementia. A year after he started Donepezil, the Dr., prescribed Memantine which also seems to he helping and he's never had any issues.
Like others have stated, everyone is different and as long as the Dr., is open to trying different medications depending on the situation, I think we should try. I do believe that after a certain stage, medications can become pointless though. My 85year old Mother has been off her medication for nearly 3 years. There has been little change with her short term memory.

posted November 14, 2021 (edited)
A myALZteam Member

I think it’s really hard to know whether they help. They don’t generally make things better, they are supposed to help slow regression. My wife had been on Namenda (or Memantine) and I think we did see some regression after she came off but she was in the later stages, and I believe these medication’s tend to be better early on. I have been told that they can cause increased confusion in later stages

posted November 14, 2021

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