Sounds a lot like the life I'm leading with LO. Remember their brain no longer defines them as the person they used to be. All memory of how things are done is gone, it's like starting over as a child, but not as charming. Don't worry about appearances, leaving his things around; just make sure he is safe and his path is clear, nothing on floor to trip over. My LO no longer understands the news reports on TV so I can't watch with him. He used to enjoy music videos, not so much now. As for the pills, I now have to grind his mood control and other important meds and mix them in a spoonful of ice cream, then mix this spoonful into 2 tablespoons of ice cream. Works great, I feel them to him, and offer water after. This is important.
As for the nightime, this is another thing I've learned: prepare everything, dinner, the bed, the pills, as soon as late afternoon, (here it starts to get dark around 5:30pm) This way you can have a normal dinner, take pills and he can be in bed by 5:30 or 5:45. It will make your life much easier to understand that night time seem to signal the end of the day, and bedtime! Hope this helps.